Finding Familial High Cholesterol Before You Know You Have It



Inherited Cholesterol Disorder Significantly Boosts Heart Risks

Untreated, the condition also makes arteries age decades faster.

By Robert Preidt, HealthDay News

Don't Miss This

Sign Up for OurHeart HealthNewsletter

Thanks for signing up!You might also like these other newsletters:

Those with genetically inherited high cholesterol were also more likely to have diseases caused by hardening of the arteries.
Those with genetically inherited high cholesterol were also more likely to have diseases caused by hardening of the arteries.
Thinkstock

People who inherit a genetic disorder that causes high levels of "bad" LDL cholesterol have an increased risk for heart disease and hardened arteries, a new study finds.

The condition is called heterozygous familial hypercholesterolemia. It's believed to affect about 1.5 million people in the United States, the researchers said.

The genes linked to this condition prevent the liver from removing LDL (low-density lipoprotein) cholesterol from the blood. This allows the bad cholesterol to build up. Doctors suspect this familial condition when LDL levels are above 190 milligrams per deciliter (mg/dL), the study authors explained.

The researchers reviewed data from six groups of people involved in previous studies. Compared to people with average LDL cholesterol levels (less than 130 mg/dL), those with familial hypercholesterolemia had a five times higher risk for heart disease.

Those with genetically inherited high cholesterol were also more likely to have diseases caused by hardening of the arteries, including earlier development of heart disease -- up to 20 years earlier in men and 30 years earlier in women, the research revealed.

RELATED: 4 Nuts That Cut Your Heart Disease Risk

Even when the researchers included other risk factors for heart disease in their analysis, the risks were still higher for those with the genetic cholesterol disorder.

The findings may help doctors explain the risks of familial hypercholesterolemia more clearly to patients. That's important because the disorder can be treated with cholesterol-lowering drugs to decrease the risks for coronary heart disease and stroke, the investigators said.

"Clinician-patient discussions about guideline-supported therapies can be informed by this data," according to the study authors, who were led by Dr. Donald Lloyd-Jones at Northwestern University in Chicago.

Using the data, doctors could present certain scenarios to their patients. For example: if a 25-year-old woman with newly diagnosed familial hypercholesterolemia leaves her cholesterol untreated, her risk of coronary heart disease death or nonfatal heart attack would be comparable to that of a 55-year-old woman, the researchers said.

"Such an analogy, paired with counseling about how to improve risk, may motivate behavioral changes as well as adoption of and adherence to evidence-based medications," the study authors said.

The findings were published June 29 in the journal Circulation.






Video: Familial Hypercholesterolemia

Inherited Cholesterol Disorder Significantly Boosts Heart Risks
Inherited Cholesterol Disorder Significantly Boosts Heart Risks images

2019 year
2019 year - Inherited Cholesterol Disorder Significantly Boosts Heart Risks pictures

Inherited Cholesterol Disorder Significantly Boosts Heart Risks recommendations
Inherited Cholesterol Disorder Significantly Boosts Heart Risks recommendations photo

Inherited Cholesterol Disorder Significantly Boosts Heart Risks pics
Inherited Cholesterol Disorder Significantly Boosts Heart Risks picture

Inherited Cholesterol Disorder Significantly Boosts Heart Risks Inherited Cholesterol Disorder Significantly Boosts Heart Risks new pics
Inherited Cholesterol Disorder Significantly Boosts Heart Risks new foto

images Inherited Cholesterol Disorder Significantly Boosts Heart Risks
photo Inherited Cholesterol Disorder Significantly Boosts Heart Risks

Watch Inherited Cholesterol Disorder Significantly Boosts Heart Risks video
Watch Inherited Cholesterol Disorder Significantly Boosts Heart Risks video

Discussion on this topic: Inherited Cholesterol Disorder Significantly Boosts Heart Risks, inherited-cholesterol-disorder-significantly-boosts-heart-risks/
Discussion on this topic: Inherited Cholesterol Disorder Significantly Boosts Heart Risks, inherited-cholesterol-disorder-significantly-boosts-heart-risks/ , inherited-cholesterol-disorder-significantly-boosts-heart-risks/

Related News


How to Read Public Court Records
10 Glam Party Bags for 2015 To Spice Up Your Outfits
How To Walk A Mile Without Leaving Home
Home Office Essentials We Just MUST Have
Mainstays Baja Futon Sofa Sleeper Bed, Multiple Colors
Zucchini with Tomato and Cheese
Every thing you need to know about pregnancy
10Everyday Actions That Make Your Skin Look10 Years Older
How One Couple Wiped Out a 125,000 Debt
How Many Types Of Vaginas Are There
5 Things That Keep You From Getting Your Zzzz’s



Date: 15.12.2018, 20:25 / Views: 44262