Off-label use of misoprostol linked to abortion deaths



Misoprostol

What Is Misoprostol?

1 Review
3 Stars

Misoprostol is the generic form of the brand-name drug Cytotec, which is used to prevent ulcers in people who take certain arthritis or pain medicines.

Drugs that can cause stomach damage include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Anaprox, Naprosen), celecoxib (Celebrex), diclofenac (Voltarin, Cataflam), indomethacin (Indocin), and meloxicam (Mobic).

Misoprostol is a synthetic prostaglandin. It works by protecting the stomach lining and decreasing stomach acid secretion.

The Food and Drug Administration (FDA) approved the medication in 1988. The drug was originally manufactured by G.D. Searle & Company, and generic forms of misoprostol are now made by several drug manufacturers.

Misoprostol and Abortion

Misoprostol is sometimes used off-label to end an early pregnancy. (Off-label use means that the FDA has not approved the drug for this purpose.)

The drug is most effective when it's used in combination with methotrexate or mifepristone. Misoprostol can be given orally, buccally (dissolved between the gums and cheek), or vaginally for this purpose.

The FDA has reported that a few women have died from severe infection after having an abortion using mifepristone and vaginal misoprostol.

You should call your doctor immediately if you experience any signs of infection, which may include weakness, pain, muscle aches, nausea, and diarrhea. This rare infection may not cause a fever.

Misoprostol is also sometimes used off-label to induce labor or decrease blood loss after delivery of a baby. However, the FDA has issued an alert about the potential dangers of using misoprostol for these purposes. The risks include a torn uterus, the need for a hysterectomy, and death of the mother and baby.

Pregnancy and Misoprostol

Misoprostolis a Pregnancy Category X drug, which means it is likely to harm an unborn baby, causing birth defects and premature birth. The drug can also harm the pregnant woman, causing uterine rupture, uterine bleeding, miscarriage, or an incomplete miscarriage. You should use an effective form of birth control while taking misoprostol and for at least one month after you stop using it.

Women shouldn't take their first dose of misoprostol until the second or third day of their menstrual period to ensure that they aren't pregnant.

It's not known whether this drug passes into breast milk or if it could harm a breastfeeding baby. You should talk to your doctor about these risks.

Misoprostol Warnings

Before taking misoprostol, you should tell your doctor if you have:

  • Inflammatory bowel disease (IBD)
  • Irritable bowel syndrome (IBS)
  • Any other intestinal problems
  • Heart disease

You should also alert your physician if you suspect you are dehydrated before taking this medicine.

This drug must be taken regularly for you to benefit. Don't stop taking misoprostol without first talking to your doctor.

Call your doctor if you experience severe nausea, stomach pain, or diarrhea lasting several days while on misoprostol.

Misoprostol Side Effects

Common Side Effects of Misoprostol

You should tell your doctor if any of the following side effects are severe or don't go away:

Serious Side Effects of Misoprostol

You should call your doctor immediately if you experience any of the side effects listed in the Warnings section or any of the following serious side effects:

  • Bloody vomit
  • Bloody or black, tarry stools
  • Any signs of infection

Misoprostol Interactions

You should always tell your doctor about any prescription, non-prescription, illegal, and recreational drugs; herbal remedies; and nutritional and dietary supplements you're taking, especially:

Misoprostol Dosage

Misoprostol comes as a tablet to take by mouth. It's typically taken four times a day, after meals and at bedtime with food.

You should follow the instructions on your prescription label carefully when taking this medicine. Don't take more or less of the drug than your doctor prescribes.

Misoprostol Overdose

Symptoms of a misoprostol overdose include the following:

  • Stomach upset or pain
  • Diarrhea
  • Trouble breathing
  • Irregular heartbeat
  • Low blood pressure
  • Tremor or seizure

If you suspect an overdose, you should contact a poison control center or emergency room immediately. You can get in touch with a poison control center at (800) 222-1222.

Missed Dose of Misoprostol

If you miss a dose of misoprostol, take it as soon as you remember.

However, if it's almost time for your next dose, skip the missed dose and continue on your regular dosing schedule. Don't take extra medicine to make up for a missed dose.

Misoprostol Pictures

Misoprostol 100 mcg-IVA, white, round,
Misoprostol 100 mcg-GRE, white, round,
Misoprostol 200 mcg-GRE, white, hexagonal,
Cytotec 100 mcg, white, round,
Misoprostol 200 mcg-IVA, white, round,
Cytotec 200 mcg, white, hexagonal,

By Lynn Marks | Medically Reviewed by Robert Jasmer, MD

Latest Update: 2015-01-29
Copyright © 2014 Everyday Health Media, LLC

About Drugs A-Z

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Basics, Side Effects, Interactions, and Dosage tabs. The information within the Reviews and FAQ tabs is proprietary to Everyday Health.

You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen.

Every effort has been made to ensure that the information provided by on this page is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. The information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy. The drug information above is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have any questions about the drugs you are taking, check with your doctor, nurse or pharmacist.






Video: Misoprost 200/Misoprostol/how to use Misoprostol at home in hindi

Misoprostol
Misoprostol images

2019 year
2019 year - Misoprostol pictures

Misoprostol forecasting
Misoprostol recommendations photo

Misoprostol photo
Misoprostol pictures

Misoprostol Misoprostol new pics
Misoprostol new foto

pics Misoprostol
photo Misoprostol

Watch Misoprostol video
Watch Misoprostol video

Forum on this topic: Misoprostol, misoprostol/
Forum on this topic: Misoprostol, misoprostol/ , misoprostol/

Related News


Stress Can Shrink Your Brain, Study Says
How to Prevent Canine Infectious Hepatitis
Sun-Dried Tomato and Feta Stuffed Artichokes
First-Time Gym Junkies: A Guide for Beginners
How to Tell if Your Partner Has a Personality Disorder
The 3 Things This Woman Does to Make 80 (Yes, 80) Look Like 50
7 Strategies To Prevent Kidney Stones
5 Moves To Boost Your Bootie
Ombre Short Hairstyles 2013
Best and worst days to travel around Christmas in 2019
Nose Job May Make You Look a Bit Younger, Too
Roast Pork Loin with Apples, Potatoes, and Sage
Miley Cyrus Can’t Believe Her 12-Year-Old Self Auditioning for HannahMontana’
Everything You Need To Know About Coconut



Date: 06.12.2018, 15:53 / Views: 65573